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doi: 10.3389/fbioe.2026.1751293 Received 21 November 2025 Revised 11 January 2026 Accepted 18 February 2026 Published 12 March 2026 Volume 14 - 2026 Edited by Yaying Sun, Shanghai General Hospital, China Reviewed by Yushu Wang, Tufts University, United States Yibo Ma, Second Affiliated Hospital of Dalian Medical University, China Updates Copyright © 2026 You, Liu, Zhang, Zheng, Dou, Yao, Li, Wang and Huang